MX-14-2
Macromolecular Crystallography 14.2
Publications
2024Scheuerer, S.; Motlova, L.; Schäker-Hübner, L.; Sellmer, A.; Feller, F.; Ertl, F.J.; Koch, P.; Hansen, F.K.; Barinka, C.; Mahboobi, S.: Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability. , European Journal of Medicinal Chemistry 276 (2024), p. 116676/1-11
doi: 10.1016/j.ejmech.2024.116676
Marino, S.F.; Daumke, O.: Structure-based humanization of a therapeutic antibody for multiple myeloma. , Journal of Molecular Medicine 102 (2024), p. 1151-1161
doi: 10.1007/s00109-024-02470-4
Buffa, V.; Meyners, C.; Sugiarto, W.O.; Bauder, M.; Gaali, S.; Hausch, F.: 1,4-Pyrazolyl-Containing SAFit-Analogues are Selective FKBP51 Inhibitors With Improved Ligand Efficiency and Drug-Like Profile. , ChemMedChem 19 (2024), p. e202400264/1-23
doi: 10.1002/cmdc.202400264
2023
Grabicki, Niklas Jan: Curved Carbon Materials : Strained Macrocycles and Photomagnetic Switches. , HU Berlin, Dissertation, 2023
doi: 10.18452/26967
Burmeister, David: Exploring graphitic carbon nitrides for (opto)electronic applications. , HU Berlin , 2023
Abylgazina, Leila: Stimuli-induced structural switchability in the pillared-layer metal-organic framework DUT-8. , TU Dresden, 2023
Dimos, Nicole: Structural and biochemical characterization of biotechnologically relevant enzymes. , FU Berlin, 2023
Felsner, Bodo: Synthese von DUT-13 und isoretikulären MOFs und Untersuchung ihrer adsorptionsinduzierten Flexibilität. , TU Dresden, 2023
Khilji, Sana Khan: The development of antibodies against tumour-associated carbohydrate antigens. , FU Berlin, 2023
Fanfrlík, J.; Brynda, J.; Kugler, M.; Lepsik, M.; Pospísilová, K.; Holub, J.; Hnyk, D.; Nekvinda, J.; Grüner, B.; Rezácová, P.: B–H⋯π and C–H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. , Physical Chemistry Chemical Physics 25 (2023), p. 1728-1733
doi: 10.1039/d2cp04673c
Kascakova, B.; Kotal, J.; Havlickova, P.; Vopatkova, V.; Prudnikova, T.; Grinkevich, P.; Kuty, M.; Chmelar, J.; Kuta Smatanova, I.: Conformational transition of the Ixodes ricinus salivary serpin Iripin-4. , Acta Crystallographica Section D - Structural biology 79 (2023), p. 409-419
doi: 10.1107/s2059798323002322
Svoboda, J.; Berdar, D.; Kolenko, P.; Cerny, J.; Novakova, Z.; Pavlicek, J.; Schneider, B.: Conformation-based refinement of 18-mer DNA structures. , Acta Crystallographica Section D - Structural biology 79 (2023), p. 655-665
doi: 10.1107/s2059798323004679
Magoch, M.; McEwen, A.G.; Napolitano, V.; Wladyka, B.; Dubin, G.: Crystal Structure of Staphopain C from Staphylococcus aureus. , Molecules (Basel) 28 (2023), p. 4407/1-10
doi: 10.3390/molecules28114407
Eisenreichova, A.; Klima, M.; Anila, M.M.; Koukalova, A.; Humpolickova, J.; Rozycki, B.; Boura, E.: Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport. , Cells 12 (2023), p. 1974/1-13
doi: 10.3390/cells12151974
Werten, S.; Waack, P.; Palm, G.J.; Virolle, M.J.; Hinrichs, W.: Crystal structures of free and ligand-bound forms of the TetR/AcrR-like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism. , FEBS Journal 290 (2023), p. 521-532
doi: 10.1111/febs.16606
Kremling, V.; Loll, B.; Pach, S.; Dahmani, I.; Weise, C.; Wolber, G.; Chiantia, S.; Wahl, M.C.; Osterrieder, N.; Azab, W.: Crystal structures of glycoprotein D of equine alphaherpesviruses reveal potential binding sites to the entry receptor MHC-I. , Frontiers in Microbiology 14 (2023), p. 1197120/1-16
doi: 10.3389/fmicb.2023.1197120
Gardonyi, M.; Hasewinkel, C.; Wallbaum, J.; Wollenhaupt, J.; Weiss, M.S.; Klebe, G.; Reuter, K.; Heine, A.: Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC. , ACS Omega 8 (2023), p. 46051-46065
doi: 10.1021/acsomega.3c07058
Purder, P.L.; Meyners, C.; Sugiarto, W.O.; Kolos, J.; Lohr, F.; Gebel, J.; Nehls, T.; Dotsch, V.; Lermyte, F.; Hausch, F.: Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues. , JACS Au : an open access journal of the American Chemical Society 3 (2023), p. 2478-2486
doi: 10.1021/jacsau.3c00241
Orsi, D.L.; Ferrara, S.J.; Siegel, S.; Friberg, A.; Bouche, L.; Pook, E.; Lienau, P.; Bluck, J.P.; Lemke, C.T.; Akcay, G.; Stellfeld, T.; Meyer, H.; Putter, V.; Holton, S.J.; Korr, D.; Jerchel-Furau, I.; Pantelidou, C.; Strathdee, C.A.; Meyerson, M.; Eis, K.; Goldstein, J.T.: Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. , Bioorganic & Medicinal Chemistry 78 (2023), p. 117130/1-14
doi: 10.1016/j.bmc.2022.117130
Geiger, T.M.; Walz, M.; Meyners, C.; Kuehn, A.; Dreizler, J.K.; Sugiarto, W.O.; Maciel, E.; Zheng, M.; Lermyte, F.; Hausch, F.: Discovery of a Potent PROTAC Enables Targeting of FKBP51's Scaffolding Functions. , Angewandte Chemie - International Edition 63 (2023), p. e202309706/1-7
doi: 10.1002/anie.202309706
Schnepel, C.; Moritzer, A.C.; Gafe, S.; Montua, N.; Minges, H.; Niess, A.; Niemann, H.H.; Sewald, N.: Enzymatic Late-Stage Halogenation of Peptides. , ChemBioChem 24 (2023), p. e202200569/1-9
doi: 10.1002/cbic.202200569
Saathoff, M.; Kosol, S.; Semmler, T.; Tedin, K.; Dimos, N.; Kupke, J.; Seidel, M.; Ghazisaeedi, F.; Jonske, M.C.; Wolf, S.A.; Kuropka, B.; Czyszczon, W.; Ghilarov, D.; Gratz, S.; Heddle, J.G.; Loll, B.; Sussmuth, R.D.; Fulde, M.: Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria. , PLoS Biology 21 (2023), p. e3002186/1-18
doi: 10.1371/journal.pbio.3002186
Kugler, M.; Hadzima, M.; Dzijak, R.; Rampmaier, R.; Srb, P.; Vrzal, L.; Voburka, Z.; Majer, P.; Rezacova, P.; Vrabel, M.: Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. , RSC Medicinal Chemistry 14 (2023), p. 144-153
doi: 10.1039/d2md00330a
Chlastakova, A.; Kascakova, B.; Kotal, J.; Langhansova, H.; Kotsyfakis, M.; Kuta Smatanova, I.; Tirloni, L.; Chmelar, J.: Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules. , Frontiers in Immunology 14 (2023), p. 1116324/1-16
doi: 10.3389/fimmu.2023.1116324
Tröster, A.; DiPrima, M.; Jores, N.; Kudlinzki, D.; Sreeramulu, S.; Grande, S.L.; Linhard, V.; Ludig, D.; Schug, A.; Saxena, K.; Reinecke, M.; Heinzlmeir, S.; Leisegang, M.S.; Wollenhaupt, J.; Lennartz, F.; Weiss, M.S.; Kuster, B.; Tosato, G.; Schwalbe, H.: Optimization of the Lead Compound NVP-BHG712 as Colorectal Cancer Inhibitor. , Chemistry - A European Journal 29 (2023), p. e202203967/1-11
doi: 10.1002/chem.202203967
Löffler, Jan Gerrit: Protein vibrational energy transfer: new sensors and application in an enzyme active site. , Uni Frankfurt, 2023
Michel, F.; Romero-Romero, S.; Höcker, B.: Retracing the evolution of a modern periplasmic binding protein. , Protein Science 32 (2023), p. e4793/1-13
doi: 10.1002/pro.4793
Sun, S.; Fushimi, M.; Rossetti, T.; Kaur, N.; Ferreira, J.; Miller, M.; Quast, J.; van den Heuvel, J.; Steegborn, C.; Levin, L.R.; Buck, J.; Myers, R.W.; Kargman, S.; Liverton, N.; Meinke, P.T.; Huggins, D.J.: Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. , Journal of Chemical Information and Modeling 63 (2023), p. 2828-2841
doi: 10.1021/acs.jcim.2c01577
Schmidt, A.; Kalms, J.; Lorent, C.; Katz, S.; Frielingsdorf, S.; Evans, R.M.; Fritsch, J.; Siebert, E.; Teutloff, C.; Armstrong, F.A.; Zebger, I.; Lenz, O.; Scheerer, P.: Stepwise conversion of the Cys6[4Fe-3S] to a Cys4[4Fe-4S] cluster and its impact on the oxygen tolerance of [NiFe]-hydrogenase. , Chemical Science 14 (2023), p. 11105-11120
doi: 10.1039/d3sc03739h
Pasch, T.; Schröder, A.; Kattelmann, S.; Eisenstein, M.; Pietrokovski, S.; Kümmel, D.; Mootz, H.D.: Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins. , Chemical Science 14 (2023), p. 5204-5213
doi: 10.1039/d3sc01200j
Job, L.; Kohler, A.; Eichinger, A.; Testanera, M.; Escher, B.; Worek, F.; Skerra, A.: Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop. , Biochemistry 62 (2023), p. 942-955
doi: 10.1021/acs.biochem.2c00666
Haldar, S.; Bhauriyal, P.; Ramuglia, A.R.; Khan, A.H.; De Kock, S.; Hazra, A.; Bon, V.; Pastoetter, D.L.; Kirchhoff, S.; Shupletsov, L.; De, A.; Isaacs, M.A.; Feng, X.; Walter, M.; Brunner, E.; Weidinger, I.M.; Heine, T.; Schneemann, A.; Kaskel, S.: Sulfide-Bridged Covalent Quinoxaline Frameworks for Lithium-Organosulfide Batteries. , Advanced Materials 35 (2023), p. 2210151/1-14
doi: 10.1002/adma.202210151
Maity, K.; Bon, V.; Kaskel, S.: Toward Controlled Partial Desolvation of Guest-Responsive Metal-Organic Frameworks for Precise Porosity Control. , Chemistry of Materials 35 (2023), p. 4192-4200
doi: 10.1021/acs.chemmater.3c00069
Hao, Y.; Velkos, G.; Schiemenz, S.; Rosenkranz, M.; Wang, Y.; Büchner, B.; Avdoshenko, S.M.; Popov, A.A.; Liu, F.: Using internal strain and mass to modulate Dy⋯Dy coupling and relaxation of magnetization in heterobimetallic metallofullerenes DyM2N@C80 and Dy2MN@C80 (M = Sc, Y, La, Lu). , Inorganic Chemistry Frontiers 10 (2023), p. 468-484
doi: 10.1039/d2qi02224a
2022
Kordes, S.; Romero-Romero, S.; Lutz, L.; Höcker, B.: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. , Protein Science 31 (2022), p. 513-527
doi: 10.1002/pro.4249
Geerds, C.; Bleymüller, W.M.; Meyer, T.; Widmann, C.; Niemann, H.H.: A recurring packing contact in crystals of InlB pinpoints functional binding sites in the internalin domain and the B repeat. , Acta Crystallographica Section D - Structural biology 78 (2022), p. 310-320
doi: 10.1107/S2059798322000432
Marjault, H.B.; Karmi, O.; Zuo, K.; Michaeli, D.; Eisenberg-Domovich, Y.; Rossetti, G.; de Chassey, B.; Vonderscher, J.; Cabantchik, I.; Carloni, P.; Mittler, R.; Livnah, O.; Meldrum, E.; Nechushtai, R.: An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters. , Communications Biology 5 (2022), p. 437/1-9
doi: 10.1038/s42003-022-03393-x
Wu, F.; Ma, J.; Lombardi, F.; Fu, Y.; Liu, F; Huang, Z.; Liu, R.; Komber, H.; Alexandropoulos, D.I.; Dmitrieva, E.; Lohr, T.G.; Israel, N.; Popov, A.A.; Liu, J.; Bogani, L.; Feng, X.: Benzo-Extended Cyclohepta[def]fluorene Derivatives with Very Low-Lying Triplet States. , Angewandte Chemie - International Edition 61 (2022), p. e202202170/1-7
doi: 10.1002/anie.202202170
Tsika, A.C.; Gallo, A.; Fourkiotis, N.K.; Argyriou, A.I.; Sreeramulu, S.; Löhr, F.; Rogov, V.V.; Richter, C.; Linard, V.; Gande, S.L.; Altincekic, N.; Krishnatas, R.; Elamri, I.; Schwalbe, H.; Wollenhaupt, J.; Weiss, M.S.; Spyroulias, G.A.: Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity. , Journal of Molecular Biology : jmb 434 (2022), p. 16772/1-21
doi: 10.1016/j.jmb.2022.167720
Malecki, P.H.; Imiolczyk, B.; Barciszewski, J.; Czyrko-Horczak, J.; Sliwiak, J.; Gawel, M.; Wozniak, K.; Jaskolski, M.; Brzezinski, K.: Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803. , Acta Crystallographica Section D - Structural biology 78 (2022), p. 865-882
doi: 10.1107/S2059798322005605
Data-doi: 10.18150/JWPKAB
Data-doi: 10.18150/1KE3PW
Data-doi: 10.18150/IRFZHN
Braun, N.J.; Huber, S.; Schmacke, L.C.; Heine, A.; Steinmetzer, T.: Boroleucine-Derived Covalent Inhibitors of the ZIKV Protease. , ChemMedChem 18 (2022), p. e202200336/1-8
doi: 10.1002/cmdc.202200336
Yang, W.; Velkos, G.; Sudarkova, S.; Büchner, B.; Avdoshenko, S.M.; Liu, F.; Popov, A.A.; Chen, N.: Carbon cage isomers and magnetic Dy⋯Dy interactions in Dy2O@C88 and Dy2C2@C88 metallofullerenes. , Inorganic Chemistry Frontiers 9 (2022), p. 5805-5819
doi: 10.1039/d2qi01796b
Kasmaei, K.M.; Kalyani, D.C.; Reichenbach, T.; Jimenez-Quero, A.; Vilaplana, F.; Divne, C.: Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. , Frontiers in Microbiology 13 (2022), p. 1050160/1-13
doi: 10.3389/fmicb.2022.1050160
Sonani, R.R.; Blat, A.; Dubin, G.: Crystal structures of apo- and FAD-bound human peroxisomal acyl-CoA oxidase provide mechanistic basis explaining clinical observations. , International Journal of Biological Macromolecules 205 (2022), p. 203-210
doi: 10.1016/j.ijbiomac.2022.02.008
Rhys, G.G.; Cross, J.A.; Dawson, W.M.; Thompson, H.F.; Shanmugaratnam, S.; Savery, N.J.; Dodding, M.P.; Höcker, B.; Woolfson, D.N.: De novo designed peptides for cellular delivery and subcellular localisation. , Nature Chemical Biology 18 (2022), p. 999–1004
doi: 10.1038/s41589-022-01076-6
Data-doi: 10.5281/zenodo.6519961
Giammarinaro, P.I.; Young, M.K.M.; Steinchen, W.; Mais, C.N.; Hochberg, G.; Yang, J.; Stevenson, D.M.; Amador-Noguez, D.; Paulus, A.; Wang, J.D.; Bange, G.: Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. , Nature Microbiology 7 (2022), p. 1442-1452
doi: 10.1038/s41564-022-01193-x
Dahms, S.O.; Schnapp, G.; Winter, M.; Buttner, F.H.; Schleputz, M.; Gnamm, C.; Pautsch, A.; Brandstetter, H.: Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism. , ACS Chemical Biology 17 (2022), p. 816-821
doi: 10.1021/acschembio.2c00103
Gilzer, D.; Schreiner, M.; Niemann, H.H.: Direct interaction of a chaperone-bound type III secretion substrate with the export gate. , Nature Communications 13 (2022), p. 2858/1-13
doi: 10.1038/s41467-022-30487-1
Dolot, R.; Maciaszek, A.; Mikolajczyk, B.; Nawrot, B.: First High-Resolution Crystal Structures of DNA:2'-O-Methyl-RNA Heteroduplexes. , Crystals (Basel) 12 (2022), p. 760/1-16
doi: 10.3390/cryst12060760
Leppkes, J.; Dimos, N.; Loll, B.; Hohmann, T.; Dyrks, M.; Wieseke, A.; Keller, B.G.; Koksch, B.: Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. , RSC Chemical Biology 3 (2022), p. 773-782
doi: 10.1039/d2cb00018k
Fietze, T.; Wilk, P.; Kabinger, F.; Anoosheh, S.; Hofer, A.; Lundin, D.; Feiler, C.G.; Weiss, M.S.; Loderer, C.: HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. , Biochemistry 61 (2022), p. 1633-1641
doi: 10.1021/acs.biochem.2c00173
Weigert, S.; Perez-Garcia, P.; Gisdon, F.J.; Gagsteiger, A.; Schweinshaut, K.; Ullmann, G.M.; Chow, J.; Streit, W.R.; Höcker, B.: Investigation of the halophilic PET hydrolase PET6 from Vibrio gazogenes. , Protein Science 31 (2022), p. e4500/1-16
doi: 10.1002/pro.4500
Zhang, J.-J.; Ma, J.; Liu, F.; Cui, L.-S.; Fu, Y.; Yang, L.; Popov, A.A.; Weigand, J.J.; Liu, J.; Feng, X.: Large Acene Derivatives with B–N Lewis Pair Doping: Synthesis, Characterization, and Application. , Organic Letters 24 (2022), p. 1877-1882
doi: 10.1021/acs.orglett.2c00033
Huskova, A.; Dinesh, D.C.; Srb, P.; Boura, E.; Veverka, V.; Silhan, J.: Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model. , Nucleic Acids Research 50 (2022), p. 10436–10448
doi: 10.1093/nar/gkac793
Dang, T.; Loll, B.; Müller, S.; Skobalj, R.; Ebeling, J.; Bulatov, T.; Gensel, S.; Göbel, J.; Wahl, M.C.; Genersch, E.; Mainz, A.; Süssmuth, R.D.: Molecular basis of antibiotic self-resistance in a bee larvae pathogen. , Nature Communications 13 (2022), p. 2349/1-11
doi: 10.1038/s41467-022-29829-w
Salerno-Kochan, A.; Horn, A.; Ghosh, P.; Nithin, C.; Koscielniak, A.; Meindl, A.; Strauss, D.; Krutyholowa, R.; Rossbach, O.; Bujnicki, J.M.; Gaik, M.; Medenbach, J.; Glatt, S.: Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26. , Langmuir 5 (2022), p. e202201418/1-17
doi: 10.26508/lsa.202201418
Data-doi: 10.17632/jvkcfwyz47.1
Loch, J.I.; Barciszewski, J.; Sliwiak, J.; Bonarek, P.; Wrobel, P.; Pokrywka, K.; Shabalin, I.G.; Minor, W.; Jaskolski, M.; Lewinski, K.: New ligand-binding sites identified in the crystal structures of beta-lactoglobulin complexes with desipramine. , IUCrJ 9 (2022), p. 386-398
doi: 10.1107/S2052252522004183
Graf, L.; Liu, F.; Naumann, M.; Büchner, B.; Krupskaya, Y.; Popov, A.A.; Knupfer, M.: Optical Anisotropy and Momentum-Dependent Excitons in Dibenzopentacene Single Crystals. , ACS Omega 7 (2022), p. 21183-21191
doi: 10.1021/acsomega.2c01987
Dietler, J.; Gelfert, R.; Kaiser, J.; Borin, V.; Renzl, C.; Pilsl, S.; Ranzani, A.T.; Garcia de Fuentes, A.; Gleichmann, T.; Diensthuber, R.P.; Weyand, M.; Mayer, G.; Schapiro, I.; Möglich, A.: Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine. , Nature Communications 13 (2022), p. 2618/1-16
doi: 10.1038/s41467-022-30252-4
Data-doi: 10.5281/zenodo.6341885
Nagel, F.; Palm, G.J.; Geist, N.; McDonnell, T.C.R.; Susemihl, A.; Girbardt, B.; Mayerle, J.; Lerch, M.M.; Lammers, M.; Delcea, M.: Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin. , International Journal of Molecular Sciences 23 (2022), p. 3468/1-14
doi: 10.3390/ijms23073468
Nagel, F.; Susemihl, A.; Geist, N.; Moehlis, K.; Palm, G.J.; Lammers, M.; Delcea, M.: Structural Basis of the Pancreatitis-Associated Autoproteolytic Failsafe Mechanism in Human Anionic Trypsin. , Journal of Inflammation Research 15 (2022), p. 3633-3642
doi: 10.2147/JIR.S367699
Bock-Bierbaum, T.; Funck, K.; Wollweber, F.; Lisicki, E.; von der Malsburg, K.; von der Malsburg, A.; Laborenz, J.; Noel, J.K.; Hessenberger, M.; Jungbluth, S.; Bernert, C.; Kunz, S.; Riedel, D.; Lilie, H.; Jakobs, S.; van der Laan, M.; Daumke, O.: Structural insights into crista junction formation by the Mic60-Mic19 complex. , Science Advances 8 (2022), p. eabo4946/1-12
doi: 10.1126/sciadv.abo4946
Scortichini, M.; Idris, R.M.; Moschütz, S.; Keim, A.; Salmaso, V.; Dobelmann, C.; Oliva, P.; Losenkova, K.; Irjala, H.; Vaittinen, S.; Sandholm, J.; Yegutkin, G.G.; Sträter, N.; Junker, A.; Müller, C.E.; Jacobson, K.A.: Structure-Activity Relationship of 3-Methylcytidine-5'-α,β-methylenediphosphates as CD73 Inhibitors. , Journal of Medicinal Chemistry 65 (2022), p. 2409-2433
doi: 10.1021/acs.jmedchem.1c01852
Koval'ova, T.; Koval, T.; Stransky, J.; Kolenko, P.; Duskova, J.; Svecova, L.; Vodickova, P.; Spiwok, V.; Benesova, E.; Lipovova, P.; Dohnalek, J.: The first structure-function study of GH151 alpha-l-fucosidase uncovers new oligomerization pattern, active site complementation, and selective substrate specificity. , FEBS Journal 289 (2022), p. 4675-5030
doi: 10.1111/febs.16387
Knejzlik, Z.; Dolezal, M.; Herkommerova, K.; Clarova, K.; Klima, M.; Dedola, M.; Zbornikova, E.; Rejman, D.; Pichova, I.: The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-beta-synthase domain. , FEBS Journal 289 (2022), p. 5571-5598
doi: 10.1111/febs.16448
Vogt, S.; Feijs, K.; Hosch, S.; De Masi, R.; Lintermann, R.; Loll, B.; Wirthmueller, L.: The superior salinity tolerance of bread wheat cultivar Shanrong No. 3 is unlikely to be caused by elevated Ta-sro1 poly-(ADP-ribose) polymerase activity. , The Plant Cell 34 (2022), p. 4130-4137
doi: 10.1093/plcell/koac261
Wehrhan, L.; Leppkes, J.; Dimos, N.; Loll, B.; Koksch, B.; Keller, B.G.: Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes - Insights from Simulation and Experiment. , The Journal of Physical Chemistry B 126 (2022), p. 9985-9999
doi: 10.1021/acs.jpcb.2c05496
2021
Kalyani, D.C.; Reichenbach, T.; Aspeborg, H.; Divne, C.: A homodimeric bacterial exo-beta-1,3-glucanase derived from moose rumen microbiome shows a structural framework similar to yeast exo-beta-1,3-glucanases. , Enzyme and Microbial Technology 143 (2021), p. 109723/1-10
doi: 10.1016/j.enzmictec.2020.109723
Dietler, J.; Schubert, R.; Krafft, T.G.A.; Meiler, S.; Kainrath, S.; Richter, F.; Schweimer, K.; Weyand, M.; Janovjak, H.; Möglich, A.: A Light-Oxygen-Voltage Receptor Integrates Light and Temperature. , Journal of Molecular Biology : jmb 433 (2021), p. 167107/1-20
doi: 10.1016/j.jmb.2021.167107
Zhang, J.; Rakhimbekova, A.; Duan, X.; Yin, Q.; Foss, C.A.; Fan, Y.; Xu, Y.; Li, X.; Cai, X.; Kutil, Z.; Wang, P.; Yang, Z.; Zhang, N.; Pomper, M.G.; Wang, Y.; Barinka, C.; Yang, X.: A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging. , Nature Communications 12 (2021), p. 5460/1-11
doi: 10.1038/s41467-021-25746-6
Data-doi: 10.2210/pdb7bfz/pdb
Ambrus, Attila: A szerkezet összefüggése a funkcióval válogatott biológiai rendszerekben = Interrelation between structure and function in selected biological systems. , Semmelweis University, Budapest, University Habilitation Thesis, 2021
You, W.; Steegborn, C.: Binding site for activator MDL-801 on SIRT6. , Nature Chemical Biology 17 (2021), p. 519-521
doi: 10.1038/s41589-021-00749-y
Lund, B.A.; Thomassen, A.M.; Carlsen, T.J.W.; Leiros, H.K.S.: Biochemical and biophysical characterization of the OXA-48-like carbapenemase OXA-436. , Acta Crystallographica Section F - Structural Biology Communications 77 (2021), p. 312-318
doi: 10.1107/S2053230X21008645
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